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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNM2
All Species:
22.42
Human Site:
Y553
Identified Species:
54.81
UniProt:
P50570
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50570
NP_001005360.1
870
98064
Y553
T
A
E
S
L
S
W
Y
K
D
E
E
E
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103119
870
98099
Y553
T
A
E
S
L
S
W
Y
K
D
E
E
E
K
E
Dog
Lupus familis
XP_542065
865
97464
Y549
T
A
E
S
L
S
W
Y
K
D
E
E
E
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P39054
870
98127
Y553
T
A
E
S
L
S
W
Y
K
D
E
E
E
K
E
Rat
Rattus norvegicus
P39052
870
98212
Y553
T
A
E
S
L
S
W
Y
K
D
E
E
E
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXN5
691
77244
E378
E
T
F
G
R
T
L
E
S
V
D
P
L
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P27619
877
97791
Y547
T
S
E
S
I
S
W
Y
K
D
E
D
E
K
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P39055
830
93389
K514
S
Q
G
Q
S
A
K
K
N
L
G
N
Q
V
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LFT2
780
86625
Q468
Q
C
M
M
K
E
L
Q
R
F
P
V
L
Q
K
Baker's Yeast
Sacchar. cerevisiae
P54861
757
84953
E445
R
P
T
L
F
V
P
E
L
A
F
D
L
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
95.1
N.A.
98.1
98
N.A.
N.A.
N.A.
N.A.
32.9
N.A.
64.4
N.A.
61.9
N.A.
Protein Similarity:
100
N.A.
100
97.2
N.A.
99
99.1
N.A.
N.A.
N.A.
N.A.
51
N.A.
76.9
N.A.
76.5
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
0
N.A.
80
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
100
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.5
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.5
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
0
10
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
60
10
20
0
0
10
% D
% Glu:
10
0
60
0
0
10
0
20
0
0
60
50
60
0
50
% E
% Phe:
0
0
10
0
10
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
0
0
0
10
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
10
10
60
0
0
0
0
50
10
% K
% Leu:
0
0
0
10
50
0
20
0
10
10
0
0
30
10
0
% L
% Met:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
10
0
0
0
0
10
0
0
0
10
10
0
0
0
% P
% Gln:
10
10
0
10
0
0
0
10
0
0
0
0
10
10
0
% Q
% Arg:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
10
0
60
10
60
0
0
10
0
0
0
0
10
0
% S
% Thr:
60
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
10
0
10
10
% V
% Trp:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _